Colostrum contains many of these

biological response modifiers.

These can be protein,peptide or

glycoprotein signaling molecules

that are used in cellular communications.

Cytokines have a specific role as

regulators of epithelial cell growth and

development, including intestinal

inflammation and epithelial restoration

following mucosal damage.

They are also important mediators

in the regulation of immune and

inflammatory responses.

Colostrum contains numerous cytokines

including :

IL-1β, IL-6, TNF-α, IFN-γ, and IL-1ra ²

These small peptide molecules are important

mediators in the regulation of immune

and inflammatory responses.

In the newborn, cytokines play an

important role in combination with the ingested

maternal immunoglobulins and non-specific

antibacterial components of colostrum.

They are major regulators of epithelial cell

growth and development, including intestinal

inflammation and epithelial restitution following

mucosal damage.